:root {
  --bg: #f7fbfa;
  --surface: #ffffff;
  --surface-soft: #edf6f3;
  --ink: #17211f;
  --muted: #52625f;
  --line: #d7e3df;
  --teal: #0b7f78;
  --teal-dark: #075d59;
  --green: #85a936;
  --coral: #c96c4a;
  --shadow: 0 24px 60px rgba(13, 51, 47, 0.12);
  --radius: 8px;
  --max: 1180px;
  color-scheme: light;
}

* {
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
}

body {
  margin: 0;
  font-family:
    Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI",
    sans-serif;
  background: var(--bg);
  color: var(--ink);
  line-height: 1.55;
}

body.nav-open {
  overflow: hidden;
}

a {
  color: inherit;
  text-decoration: none;
}

img,
svg {
  display: block;
  max-width: 100%;
}

.skip-link {
  position: absolute;
  left: 1rem;
  top: 0.75rem;
  z-index: 20;
  transform: translateY(-160%);
  background: var(--ink);
  color: white;
  padding: 0.55rem 0.8rem;
  border-radius: var(--radius);
}

.skip-link:focus {
  transform: translateY(0);
}

.visually-hidden {
  position: absolute;
  width: 1px;
  height: 1px;
  padding: 0;
  margin: -1px;
  overflow: hidden;
  clip: rect(0, 0, 0, 0);
  white-space: nowrap;
  border: 0;
}

.site-header {
  position: fixed;
  inset: 0 0 auto;
  z-index: 10;
  display: flex;
  align-items: center;
  justify-content: space-between;
  width: min(calc(100% - 2rem), var(--max));
  margin: 1rem auto 0;
  padding: 0.7rem 0.8rem;
  border: 1px solid rgba(215, 227, 223, 0.86);
  border-radius: var(--radius);
  background: rgba(247, 251, 250, 0.86);
  backdrop-filter: blur(18px);
  transition: box-shadow 180ms ease, background 180ms ease;
}

.site-header.is-scrolled {
  background: rgba(255, 255, 255, 0.94);
  box-shadow: 0 14px 40px rgba(23, 33, 31, 0.08);
}

.brand {
  display: inline-flex;
  align-items: center;
  gap: 0.65rem;
  min-width: 0;
  font-weight: 760;
  font-size: 1.05rem;
}

.brand span {
  white-space: nowrap;
}

.site-nav {
  display: flex;
  align-items: center;
  gap: 0.25rem;
}

.site-nav a {
  padding: 0.55rem 0.85rem;
  border-radius: var(--radius);
  color: var(--muted);
  font-size: 0.94rem;
  font-weight: 650;
}

.site-nav a:hover,
.site-nav a:focus-visible {
  background: var(--surface-soft);
  color: var(--ink);
  outline: none;
}

.nav-toggle {
  display: none;
  width: 42px;
  height: 42px;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: var(--surface);
  color: var(--ink);
  padding: 0;
}

.nav-toggle span:not(.visually-hidden) {
  display: block;
  width: 18px;
  height: 2px;
  margin: 4px auto;
  background: currentColor;
  border-radius: 99px;
}

.hero {
  position: relative;
  isolation: isolate;
  display: grid;
  grid-template-columns: minmax(0, 1.1fr) minmax(280px, 0.42fr);
  align-items: end;
  min-height: 92svh;
  padding: clamp(7rem, 11vw, 10rem) max(1rem, calc((100vw - var(--max)) / 2)) 3rem;
  gap: clamp(1.5rem, 4vw, 4rem);
  overflow: hidden;
}

.hero::before {
  content: "";
  position: absolute;
  inset: auto 0 0;
  height: 34%;
  z-index: -2;
  background: linear-gradient(0deg, rgba(237, 246, 243, 0.95), rgba(237, 246, 243, 0));
}

.hero-visual {
  position: absolute;
  inset: 5rem 0 auto auto;
  z-index: -1;
  width: min(60vw, 780px);
  opacity: 0.95;
}

.hero-content {
  max-width: 780px;
}

.eyebrow {
  margin: 0 0 0.8rem;
  color: var(--teal-dark);
  font-size: 0.78rem;
  font-weight: 800;
  text-transform: uppercase;
}

h1,
h2,
h3,
p {
  margin-top: 0;
}

h1 {
  max-width: 830px;
  margin-bottom: 1.25rem;
  font-size: clamp(3rem, 8vw, 7.4rem);
  line-height: 0.95;
  font-weight: 820;
}

h2 {
  margin-bottom: 0;
  font-size: clamp(2rem, 4vw, 4.4rem);
  line-height: 1;
  font-weight: 790;
}

h3 {
  margin-bottom: 0.55rem;
  font-size: clamp(1.2rem, 1.8vw, 1.55rem);
  line-height: 1.12;
}

.hero-copy {
  max-width: 670px;
  color: var(--muted);
  font-size: clamp(1.05rem, 1.65vw, 1.34rem);
}

.hero-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 0.8rem;
  margin-top: 2rem;
}

.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 48px;
  padding: 0.85rem 1.05rem;
  border: 1px solid transparent;
  border-radius: var(--radius);
  font-weight: 760;
}

.button-primary {
  background: var(--teal);
  color: white;
}

.button-primary:hover,
.button-primary:focus-visible {
  background: var(--teal-dark);
}

.button-secondary {
  background: rgba(255, 255, 255, 0.7);
  border-color: var(--line);
  color: var(--ink);
}

.button-secondary:hover,
.button-secondary:focus-visible {
  background: white;
}

.hero-panel {
  padding: 1.25rem;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: rgba(255, 255, 255, 0.78);
  box-shadow: var(--shadow);
  backdrop-filter: blur(16px);
}

.scientific-panel {
  align-self: center;
  padding: 0;
  overflow: hidden;
  background:
    linear-gradient(145deg, rgba(255, 255, 255, 0.92), rgba(237, 246, 243, 0.86)),
    var(--surface);
  box-shadow: 0 28px 80px rgba(13, 51, 47, 0.16);
}

.analysis-visual {
  width: 100%;
  aspect-ratio: 420 / 360;
}

.analysis-field {
  fill: rgba(255, 255, 255, 0.58);
  stroke: rgba(11, 127, 120, 0.18);
  stroke-width: 1;
}

.analysis-glow {
  fill: none;
  stroke: rgba(11, 127, 120, 0.1);
  stroke-width: 42;
  stroke-linecap: round;
}

.sequence-reads,
.helix,
.signal-line,
.variant-grid {
  fill: none;
  stroke-linecap: round;
  stroke-linejoin: round;
}

.sequence-reads {
  stroke: rgba(23, 33, 31, 0.28);
  stroke-width: 4;
}

.read-marks {
  fill: rgba(183, 216, 107, 0.9);
}

.helix path:nth-child(-n + 2) {
  fill: none;
  stroke: url("#signal-gradient");
  stroke-width: 5;
  stroke-linecap: round;
}

.helix path:nth-child(n + 3) {
  fill: none;
  stroke: rgba(23, 33, 31, 0.26);
  stroke-width: 2;
  stroke-linecap: round;
}

.signal-line {
  stroke: url("#signal-gradient");
  stroke-width: 6;
}

.variant-points {
  fill: var(--surface);
  stroke: var(--teal);
  stroke-width: 3;
}

.variant-points circle:nth-child(2n) {
  stroke: #b7d86b;
}

.variant-points circle:nth-child(3n) {
  stroke: #e39a78;
}

.variant-grid {
  stroke: rgba(23, 33, 31, 0.16);
  stroke-width: 1;
}

.variant-cells {
  fill: rgba(11, 127, 120, 0.2);
}

.variant-cells rect:nth-child(2n) {
  fill: rgba(133, 169, 54, 0.24);
}

.hero-panel p {
  color: var(--muted);
  margin-bottom: 1rem;
}

.hero-panel p:last-child {
  margin-bottom: 0;
}

.panel-label {
  color: var(--ink) !important;
  font-size: 0.78rem;
  font-weight: 820;
  text-transform: uppercase;
}

.section {
  padding: clamp(4rem, 8vw, 7rem) max(1rem, calc((100vw - var(--max)) / 2));
}

.section-heading {
  display: grid;
  grid-template-columns: minmax(0, 0.38fr) minmax(0, 0.62fr);
  gap: clamp(1rem, 3vw, 3rem);
  align-items: start;
  margin-bottom: clamp(2rem, 5vw, 4rem);
}

.section-intro {
  background: var(--surface);
}

.focus-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1rem;
}

.focus-card,
.contact-card {
  padding: clamp(1.1rem, 2vw, 1.45rem);
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: var(--surface);
}

.focus-card {
  min-height: 300px;
}

.focus-card p,
.approach-copy,
.contact-card a,
.site-footer p {
  color: var(--muted);
}

.icon {
  display: inline-grid;
  place-items: center;
  width: 48px;
  height: 48px;
  margin-bottom: 1.4rem;
  border-radius: var(--radius);
  background: var(--surface-soft);
  color: var(--teal);
}

.icon svg {
  width: 25px;
  height: 25px;
  fill: none;
  stroke: currentColor;
  stroke-width: 1.8;
  stroke-linecap: round;
  stroke-linejoin: round;
}

.partner-band {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(280px, 0.7fr);
  gap: clamp(2rem, 6vw, 5rem);
  align-items: center;
  background: #17211f;
  color: white;
}

.partner-band .eyebrow {
  color: #9fd6d1;
}

.partner-list {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 0.75rem;
  margin: 0;
  padding: 0;
  list-style: none;
}

.partner-list li {
  min-height: 54px;
  padding: 0.95rem 1rem;
  border: 1px solid rgba(255, 255, 255, 0.15);
  border-radius: var(--radius);
  background: rgba(255, 255, 255, 0.07);
  color: rgba(255, 255, 255, 0.84);
  font-weight: 720;
}

.approach {
  background: var(--surface-soft);
}

.approach-layout {
  display: grid;
  grid-template-columns: minmax(0, 0.78fr) minmax(280px, 0.42fr);
  gap: clamp(1.5rem, 5vw, 4rem);
}

.approach-copy {
  max-width: 720px;
  font-size: clamp(1.1rem, 1.6vw, 1.35rem);
}

.principles {
  display: grid;
  gap: 0.75rem;
}

.principles div {
  display: grid;
  grid-template-columns: 3.2rem 1fr;
  gap: 1rem;
  align-items: center;
  padding: 1rem;
  border: 1px solid var(--line);
  border-radius: var(--radius);
  background: rgba(255, 255, 255, 0.72);
}

.principles span {
  color: var(--coral);
  font-weight: 840;
}

.principles p {
  margin: 0;
  font-weight: 760;
}

.contact-section {
  background: var(--surface);
}

.contact-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1rem;
}

.contact-card {
  min-height: 230px;
}

.role {
  margin-bottom: 1rem;
  color: var(--coral);
  font-weight: 820;
}

.contact-card a {
  display: table;
  margin-top: 0.5rem;
}

.contact-card a:hover,
.contact-card a:focus-visible {
  color: var(--teal-dark);
  text-decoration: underline;
  text-underline-offset: 0.18em;
}

.site-footer {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 1.5rem;
  padding: 1.3rem max(1rem, calc((100vw - var(--max)) / 2));
  border-top: 1px solid var(--line);
  background: var(--bg);
}

.footer-details {
  display: grid;
  gap: 0.2rem;
}

.footer-details p {
  margin: 0;
  text-align: right;
  font-size: 0.92rem;
}

@media (max-width: 860px) {
  .site-header {
    width: calc(100% - 1rem);
    margin-top: 0.5rem;
  }

  .nav-toggle {
    display: block;
  }

  .site-nav {
    position: fixed;
    left: 0.5rem;
    right: 0.5rem;
    top: 4.75rem;
    display: grid;
    gap: 0.35rem;
    padding: 0.7rem;
    border: 1px solid var(--line);
    border-radius: var(--radius);
    background: white;
    box-shadow: var(--shadow);
    opacity: 0;
    pointer-events: none;
    transform: translateY(-0.5rem);
    transition: opacity 160ms ease, transform 160ms ease;
  }

  .site-nav.is-open {
    opacity: 1;
    pointer-events: auto;
    transform: translateY(0);
  }

  .site-nav a {
    padding: 0.85rem;
  }

  .hero {
    grid-template-columns: 1fr;
    min-height: auto;
    padding-top: 7rem;
  }

  .hero-visual {
    inset: 5rem -8rem auto auto;
    width: 560px;
    opacity: 0.75;
  }

  .hero-panel {
    max-width: 560px;
  }

  .section-heading,
  .partner-band,
  .approach-layout {
    grid-template-columns: 1fr;
  }

  .focus-grid,
  .contact-grid {
    grid-template-columns: 1fr;
  }

  .focus-card {
    min-height: 240px;
  }
}

@media (max-width: 560px) {
  h1 {
    font-size: clamp(2.45rem, 12vw, 3.05rem);
    line-height: 1.02;
  }

  .hero-actions,
  .button {
    width: 100%;
  }

  .partner-list {
    grid-template-columns: 1fr;
  }

  .site-footer {
    align-items: flex-start;
    flex-direction: column;
  }

  .site-footer p {
    text-align: left;
  }
}

@media (prefers-reduced-motion: reduce) {
  *,
  *::before,
  *::after {
    scroll-behavior: auto !important;
    transition-duration: 0.01ms !important;
    animation-duration: 0.01ms !important;
    animation-iteration-count: 1 !important;
  }
}